THREAD: Factual details on sex chromosomes and rare genetic variations to the normal XX female and XY male.
Sex is biological and 99.98 percent of humans are either straight up male or female with no ambiguities.
It's determined at conception and fertilization, and is observable in every cell, every system, all our hormones, every organ, and in our entire biology. Sex is not assigned. Sex is observed as a physical, material and biological fact.
Ultimately it's all about the gametes. If you produce sperm you are male. If you produce ova you are female. No human was ever born without the haploid contribution of both male and female gametes.
And as regards intersex, this occurs in about 0.017 percent of humans and every case is a disorder of sexual development of either a male or a female. We have a ton of good data and the DSD categories are well understood genetically.
The 6 biological karyotype sex disorders that don’t result in death to the fetus:
XX Normal Female
XY Normal Male
XXY intersex Male: 1 in 500-1,000 births (Klinefelter Syndrome)
XYY Intersex Male: 1 in 1,000 births
X intersex Female: 1 in 2,000-5,000 births (Turner’s Syndrome)
XXXY – Intersex Male: 1 in 18,000-50,000 births
If you are 46,XX you are female with MRKH Syndrome. If you are 45,XO you are still female, but with Turner syndrome. And, 47XXX, 48XXXX and 49XXXXX aren't a spectrum of femaleness. These are classified as female chromosomal disorders.
If you are 46,XY you are male. If you are 47XXY you are male with Klinefelter syndrome. If you are 48, XXYY you are male with XXYY syndrome. Syndromes for 48,XXXY and 49,XXXXY are all still male. These aren't on a spectrum - they are categorized as male genetic disorders.
If someone had Trisonomy 21, we don't say they are on a human spectrum of any sort, we classify them as having Downs syndrome.
Intersex conditions can exist on a spectrum, but only in r/t to the severity of that specific condition. However, even over that spectrum there are defined sex categories. Ie, Androgen insensitivity syndrome is someone who is male, but their Repro organs didn't fully develop.
It has 3 categories of severity. There is no spectrum gradient between male and male with androgen insensitivity syndrome. These are clearly defined categories. There is no spectrum gradient between female and androgen insensitivity syndrome.
You are either in the category female or category male with androgen insensitivity syndrome. There is NO spectrum gradient or overlap between having an intersex genetic abnormality and being a normal XX female / normal XY male.
If you have all the typical indicators of your sex then you are that sex and you are in that category.
If you are born with the number and type of sex chromosomes off from your external genitalia with unmatching or mixed type of gonads or with ambiguous internal reproductive anatomy; and/or ambiguous external genitalia, then you are in the intersex category.
Bottom line: Intersex is a specific set of individual genetic disorders of sexual development. So, intersex conditions do not qualify as a third sex or a collection of different sexes.
Gender on the other hand is a set of trivial characteristics associated with the performance of masculine or feminine behaviors. These are entirely cultural constructs and are widely varied from culture to culture.
Typically, gender is how the social hierarchy box constructed in patriarchal societies limits the power of females. If you don't understand the ways that male transactivists are consciously and intentionally infringing the rights of women then you have not been paying attention
Either that or you are purposely blind to the intensely violent misogyny now being directed at women from that population cohort.
Bottom line is there are two sexes, three orientations and 7.6 billion genders (as many as there are people). Rocks are hard. Water is wet. Men are not women. Women are not men. Nobody is ever born into the wrong body.
Nobody should be discriminated against and no one should care about any particular person's gender performance. That's all gender is... it's not biology. It's just a performance of gendered masculinity or gendered femininity and should not be confused with sex.
Please feel free to copy and save this. It's complex and difficult to remember off the top of your head if you do not know the biology inside and out. And lots of people will try to confuse you with their ideological bullshit. The science is clear and the data is not confused
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