The 3 main risks to the vaccines being a panacea narrative has been:

1) execution - we got this today
2) adoption/usage - ongoing
3) a variant strain

#3 would be the most shocking. But the fact is the documented case of reinfection was result of infection with a variant strain
Mutated strain that is more contagious hitting UK hopefully current vaccines are effective on it and whatever mutations are to come. https://amp.theguardian.com/world/2020/dec/14/how-a-new-covid-strain-may-have-spread-virus-in-south-of-england
Here is a good thread on genetic mutations and specifically covid19 mutations. Also, if you ever wondered about genetic algorithms, same thing. https://twitter.com/drkiki/status/1340393526979268608?s=21
Here’s a great thread on the current mutation, and a little concerning where one “tweak” occured as it relates to immunity/ vaccine. https://twitter.com/drericding/status/1341314702308196353?s=21
Unfortunetly it looks like early reports, are gaining credibility, that the South African strain being resistant to immune response from previous infection and the approved vaccines. https://twitter.com/drericding/status/1352058546163249152?s=21
Good news x2 current vaccine is within protective scope of vaccine.

Additionally, there’s more attention on eventual need for boosters and required logistics to monitor, develop and distribute for new variant strains. https://twitter.com/moderna_tx/sta 
Here’s a good thread on distribution of the variant strains. https://twitter.com/angie_rasmussen/status/1354962241976586250?s=21
You can follow @MattGarrett3.
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